Uses:

Benzathine benzylpenicillin is a long-acting benzylpenicillin salt with the same antimicrobial action as benzylpenicillin. It gives bloodlevels for 2 - 4 weeks after the injection, but much lower than benzylpenicillin sodium. It is therefore restricted to highly susceptible micro-organisms. Acute infections should be treated initially with benzylpenicillin sodium. Benzathine benzylpenicillin is an antibiotic which is effective in streptococcal, pneumococcal and treponemal infections. It is used in the treatment of infections which are highly sensitive to penicillin and which require longterm treatment: syphilis, pneumonia, leptospirosis, yaws and pinta.

Prevention of rheumatic fever.

Dosage:

Administer by deep intramuscular injection.

Contra-indications and warnings:

Do not use in patients with known penicillin allergy. Use only with care in patients with renal impairment. Concomitant use of probenecid, indometacine and salicylates in high doses reduces excretion of penicillins.